Tiberal (Ro 7-0207-Roche) in the Treatment of Intestinal Amoebiasis - Part II

  • Sunoto Sunoto Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • S. H. Pudjiadi Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Suharjono Suharjono Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Z. Sulaiman Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
DOI: https://doi.org/10.14238/pi16.9-10.1976.403-11
Keywords: tiberal; intestinal amoebiasis; amoebicid; metronidazole

Abstract

Twenty-four intestinal amoebiasis patients have been treated with a new amoebicid tiberal (Roche) or metronidazole as a control in a dosage of 15- 30 mg/kg body weight per day for 5 consecutive days. The results show that both drugs achieve a 100% cure rate. No side effects or signs of drug toxicity as evaluated from the results of the safety tests were observed. No signs of clinical or parasitological relapses were seen (after discharge. In comparison with the previous trial with a lower dosage (7~ - 15 mg.) and longer course (7 days) the results were even better, e.g. clinical improvement and parasitological disappearance were achieved in a shorter time.

References

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3. PUDJIADI, S.H.; SRI MULJANI DARMAWAN and MUSLICHAN, S. : lntestopan in the treatment of intestinal amoebiasis. Paediatr. Indones. 9 : 137 (1969).
4. PUD)IADI, S.H.; SUNOTO; SUHARJONO and NARTONO KADRI : A new oral amoebicid (Ro 7-0207) in the treatment of intestinal amoebiasis. Asian J. Med. 8 : 528 (1972).
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Published
2019-09-18
How to Cite
1.
Sunoto S, Pudjiadi SH, Suharjono S, Sulaiman Z. Tiberal (Ro 7-0207-Roche) in the Treatment of Intestinal Amoebiasis - Part II. PI [Internet]. 18Sep.2019 [cited 18Apr.2024];16(9-10):403-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2318
Issue
Vol 16 No 9-10 (1976): September - October 1976
Section
Infection & Tropical Pediatrics

Copyright (c) 2019 Sunoto Sunoto, S. H. Pudjiadi, Suharjono Suharjono, Z. Sulaiman

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Received 2019-09-18
Published 2019-09-18