The Use of Anthelmintics in the Treatmenlt of Ascariasis

Authors

  • Djauhar Ismail Departments of Child Health and Parasitology, Medical School, University of Gadjah Mada, Yogyakarta, Central Java
  • Utomo Utomo Departments of Child Health and Parasitology, Medical School, University of Gadjah Mada, Yogyakarta, Central Java
  • Sugeng Yuwono Departments of Child Health and Parasitology, Medical School, University of Gadjah Mada, Yogyakarta, Central Java
  • Noerhayati S. Departments of Child Health and Parasitology, Medical School, University of Gadjah Mada, Yogyakarta, Central Java

DOI:

https://doi.org/10.14238/pi16.9-10.1976.391-5

Keywords:

anthelmintic; ascariasis; piperazine; tetramisole; pyrantel pamoate;

Abstract

Ninety-seven children with Ascariasis were treated at randomly with Piperazine, Tetramisole, and Pyrantel pamoate in a single dose with cure rates of 59%, 62%, and 88%, respectively. In the children who were not cured, a reduction in egg count of nearly 80% was found in all three treatment groups. The results of this study showed that Pyrantel pamoate is the most effective of the three drugs.

References

1. BELL, W.J. and NASSIF, S. : Comparison of Pyrantel pamoate and Piperazine phosphate in the trerutment of Ascariasis. J. trop. Med. Hyg. 20 : 584 (1971).
2. CHANCO, P.P.; CABE, E. and VIDAD, Ma., J.J. Y. : The efficacy of Pyrantel pamoate iJn the treatment
of Ascariasis (a comparative study with Piperazine and Tetramisole). Proceeding on the lOth Southeast
Asian Regional Seminar on Tropical Medicine, Bangkok, October 26-30, 1971.
3. HSIEH, M.G. and CHEN, E.R. : Evaluation of Anthelmilntic activity of Pyrantel pamoate (Combantrin) against Ascaris and Hookworm. Chin. J. Microbiol. 3 : 126 (1970).
4. KOSIN, E. : Some aspects on the treatment of Ascariasis and Hookworm infection in North Sumatra. Abstract. Seminar on Public Health Research. Jakarta, July 31-August 3, 1973.
5. RIM, H.J. rund LIM, J.K. : Treatment of Enterobiasis and Ascariasis with Combantrin. Proceeding on the 10th Southeast Asian Regional Seminar on Tropical Medicine, Bangkok, October 26-30, 1971.
6. SEFTEL, H.C. and HEINZ, H.J.; Comparison on Piperazine and Tetramisole in treatment of Ascariasis. Br.
Med. J . 4 : 93 (1968).
7. W.H.O. Expert Committee : Control of Ascariasis. W.H.O. Tech. Rep. Ser. 879 (1967).

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Published

2019-09-18

How to Cite

1.
Ismail D, Utomo U, Yuwono S, S. N. The Use of Anthelmintics in the Treatmenlt of Ascariasis. PI [Internet]. 2019Sep.18 [cited 2025Apr.20];16(9-10):391-5. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2316

Issue

Vol. 16 No. 9-10 (1976): September - October 1976

Section

Infection & Tropical Pediatrics

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