Neonatal Tetanus Evaluation of Treatment and a Proposal for Classification of Severity

  • Tjandra Husada Department of Child Health, Universitas Sam Ratulangi/Gunung Wenang Hospital, Manado, North Sulawesi
  • T. H. Rampengan Department of Child Health, Universitas Sam Ratulangi/Gunung Wenang Hospital, Manado, North Sulawesi
  • Ign. Harjanto Department of Child Health, Universitas Sam Ratulangi/Gunung Wenang Hospital, Manado, North Sulawesi
  • I. D. Arif Department of Child Health, Universitas Sam Ratulangi/Gunung Wenang Hospital, Manado, North Sulawesi
  • Muzief Munir Department of Child Health, Universitas Sam Ratulangi/Gunung Wenang Hospital, Manado, North Sulawesi
Keywords: neonatal tetanus; antitetanus serum; diazepam;

Abstract

An evaluation was made on 22 neonates with Tetanus Neonatorum (age 5 - 21 days), who were admitted to the Military Hospital, Teling, Manado, in 1973. Seventeen of our patients were babies born in their homes and were delivered by the "dukun kampong"; 5 babies were born in the maternity clinic and were helped by midwives.

The therapy given were :

  1. Anti-Tetanus serum 10,000 U, single dose, given immediately on admission.
  2. Procain Penicilline 100,000 U/kg. b.w./day; i.m. divided into 2 equal doses for 10 days.
  3. Diazepam (valium) 5 mg./kg. b.w./day; oral, divided into 8 equal doses, and 2.5 mg, parenterally 4 times a day.

References

1. ALHADY, S.M.A. : Total paralysis regime in severe tetanus. Br. med. J. 1 : 540 - 545 (1960). Cited by Kloetzel (1963).
2. ANTAVALE, V.B. and PAI P.N. : J. pediatr. 67 : 649 (1965). Cited by Salimpur (1971).
3. A YIM, E.M. Cited by Schofield (1973).
4. BARTEN, J.: Neonatal tetanus in Indonesia. Trop. Doc. 3 : 107 (1973).
5. BYTCHENKO, B. : Geographical distribution of tetanus in the world, 1951-60; a review of the problem. Bull. W.H.O. 34: 71-104 (1966) .
6. CHEAH, P.S.; MAH. P.K.; and FENG, P.H. : Severe tetanus successfully treated with high dose of diazepan (Valium) and propranolol; a case report. Singapore. med. J. 13 : 163 (1972).
7. COLE, L.B. : Tracheostomy in tetanus. Proc. r. Soc. med. 52 : 411-12 (1959).
8. CONN, H.F. : Current therapy, p. 57 (Saunders, Philadelphia/ London 1962).
9. DAILI, S.; JAHJA, S.; and ASNIL, P.O.: Valium as anticonvulsnnt in tetanus. Paediatr. Indones. 12 : 229 (1972).
10. FEMI-PEARS. D. Experience with diazepam in tetanus. Br. med. J. 2 : 862-865 (1966).
11. JELLIFFE, D.B.: Diseases of children in the subtropics and tropics. 2nd ed., p. 650 (Arnold, London 1970).
12. JENKINS, H.T. and LUI-IN, N.R.: Anesthesiology. 23 : 6'-)0 (1962). Cited by Femi-Pears ( 1966).
13. JO KIAN TJAY :mel LEMAN SEMBIRING: Modified treatment on neonates tetanus. Paediatr. Indones. 12 : 281 ( 1972).
14. KLOLTZFL, K. Clinical patterns in severe tetanus. J Am. med. Assoc. 559 (1963).
Published
2019-09-17
How to Cite
1.
Husada T, Rampengan TH, Harjanto I, Arif ID, Munir M. Neonatal Tetanus Evaluation of Treatment and a Proposal for Classification of Severity. PI [Internet]. 17Sep.2019 [cited 26Apr.2024];16(9-10):345-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2309
Section
Infection & Tropical Pediatrics
Received 2019-09-17
Published 2019-09-17