Low birth weight profiles at H. Boejasin Hospital, South Borneo, Indonesia in 2010-2012
Abstract
Background The prevalence of low birth weight (LBW) is still high in Indonesia. Intrauterine growth restriction (IUGR) and prematurity are the most frequent causes. Prematurity has higher mortality rate. Cultural diversity has an impact on regional LBW profiles in Indonesia. However, data on LBW is unavailable in South Borneo.
Objective To describe the LBW profiles and in-hospital mortality of newborns at H. Boejasin Hospital, South Borneo.
MethodsThis was a cross-sectional study using secondary data from medical records and neonatal registry at H. Boejasin Hospital, Pelaihari, South Borneo from 2010 to 2012. Subjects were newborns with birth weight <2,500 grams. Categorical data was presented in percentages, while survival analysis was assessed by Kaplan-Meier test. The difference among groups was analyzed with log-rank test.
Results The proportion of LBW was 20.2% of total live births and the mortality rate was 17.3%. Mortality rates according to birth weight category was 96% in <1000 g group, 62% in 1,000-1,499 g group, 19% in 1,500-1,999 g group, and 4% in 2,000-2,499 g group. The highest hazard ratio was in the <1,000 gram birth weight group (HR 40.21), followed by the 1,000-1,499 gram group (HR 12.95), and the 1,500-1,999 gram group (HR 4.65);(P<0.01). Asphyxia, hyaline membrane disease (HMD), and sepsis were the most common causes of mortality (at 50%, 21%, and 16%, respectively).
Conclusion The prevalence of LBW in this study is quite high and mortality of LBW infants is significantly different between each low birth weight category. [Paediatr Indones. 2016;56:155-61.].
References
2. Pudjiadi AH, Hegar B, Handryastuti S, Idris NS, Gandaputra EP, Harmoniati ED [editors]. Bayi berat lahir rendah. In: Pedoman Pelayanan Medis IDAI. Jakarta: PP IDAI; 2010. p.23-8.
3. Balitbang Kemenkes RI. Riset Kesehatan Dasar 2013. Jakarta: Kemenkes RI; 2013. p. 107-8
4. Institute of Medicine (US) Committee on Improving Birth Outcomes.The problem of low birth weight. In: Bale JR, Stoll BJ, Lucas AO, editors. Improving birth outcomes: meeting the challenge in the developing world. Washington DC: National Academic Press; 2003. p. 134-6.
5. World Health Organization. Maternal anthropometry and pregnancy outcomes: A WHO Collaborative Study. Bull World Health Organ. 1995;73:1-98.
6. UNICEF. Neonatal mortality rates. 2015 [cited 2015 Jan 10]. Available from: http://data.unicef.org/child-survival/neonatal.
7. Endaryani B. Perawatan metode kangguru (PMK) meningkatkan pemberian ASI. 2014 [cited 2015 Jan 10]. Available from: http://www.idai.or.id/artikel/klinik/asi/perawatan-metode-kanguru-pmk-meningkatkan-pemberian-asi.
8. UCSF Children’s Hospital at UCSF Medical Centre. Very low extremely low birthweight infants. California:University of California; 2004. p. 65-8.
9. Mbazor OJ, Umeora OU. Incidence and risk factors for low birth weight among term singletons at the University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. Niger J Clin Pract. 2007;10:95-9.
10. Lubchenco LO, Searls DT, Brazie JV. Neonatal mortality rate: relationship to birth weight and gestational age. J Pediatr. 1972;8:814-22.
11. Kramer MS. Determinants of low birth weight: methodological assessment and meta-analysis. Bull World Health Organ. 1987;65:663-737.
12. Institute of Medicine (IOM). Nutrition issues in developing countries part II: diet and activity during pregnancy and lactation. Washington DC: National Academy Press; 1992. p. 98-103.
13. Prentice AM, Whitehead RG, Watkinson M, Lamb WH, Cole TJ. Prenatal dietary supplementation of African women and birth weight. Lancet. 1983:1;489-92.
14. Launer LJ, Villar J, Kestler E, de Onis M. The effect of maternal work on fetal growth and duration of preganancystudy: a prospective study. Br J Obstet Gynaecol. 1990;97:62-70.
15. Sulaiman S, Othman S, Razali N, Hassan J. Obstetrics and perinatal outcome in teenage pregnancies. S African J Obstet Gynaecol. 2013;19:77-9.
16. BPS Tanah Laut. Jumlah sekolah, murid, dan guru sekolah dasar menurut kecamatan 2013. [cited2015 Jan 10]. Available from:http://tanahlautkab.bps.go.id/ ?set=viewDataDetail&flag_template2=1&id_sektor= 54&id_subsektor=54&id=176
17. BPS. Angkapartisipasisekolah (APS) menurutprovinsitahun 2003-2013. [cited 2015 Jan 10]. Available from: http://www.bps.go.id/tab_sub/view.php?kat=1&tabel=1&daftar=1&id_subyek=28¬ab=3.
18. Yasmin S, Osrin D, Paul E, Costello A. Neonatal mortality of low-birth-weight infants in Bangladesh. Bull World Health Organ. 2001;79:608-14.
19. Morales P, Bustamante D, Espina-Marchant P, Neira-Peña T, Gutierrez-Hernandez MA, Allende-Castro C, et al. Pathophysiology of perinatal asphyxia: can we predict and improve individual outcomes? EPMA J. 2011;2:211-30.
20. Caserta MT. Neonatal sepsis (sepsis neonatorum). [cited 2014 December 20].Available from:http://www.merckmanuals.com/professional/pediatrics/infections_in_neonates/neonatal_sepsis.html.
21. Iliodromiti S, Mackay DF, Smith GCS, Pell JP, Nelson SM. Apgar score and the risk of cause-specific infant mortality: a population-based cohort study. Lancet.2014;384:1749–55.
22. Katz J, Lee AC, Kozuki N, Lawn JE, Cousens S, Blencowe H, et al. Mortality risk in preterm and small-for-gestational-age infants in low-income and middle-income countries: a pooled country analysis. Lancet. 2013;382:417–25.
23. Kozuki N, Katz J, LeClerq SC, Khatry SK, West KP Jr, Christian P. Risk factors and neonatal/infant mortality risk of small-for-gestational-age and preterm birth in rural Nepal. J Matern Fetal Neonatal Med. 2015;28:1019-25.
24. Raju U, Dayal SS. Nosocomial infections in the NICU. In: Gupte S, Gupte SB, editors. Recent advances in pediatrics: neonatal and pediatric intensive care. 1st ed. London: Jaypee Brothers Medical Publishers; 2011. p. 221-36.
25. Tavora AC, Castro AB, Militao MA, Girao JE, Ribeiro Kde C, Tavora LG. Risk factors for nosocomial infection in a Brazilian neonatal intensive care unit.Braz J Infect Dis. 2008;12:75-9.
26. Mwansa-Kambafwile J, Cousens S, Hansen T, Lawn JE. Antenatal steroids in preterm labour for the prevention of neonatal deaths due to complications of preterm birth. Int J Epidemiol. 2010;39:i122–33.
27. Pattanittum P, Ewens MR, Laopaiboon M, Lumbiganon P, McDonald SJ, Crowther CA, et al. Use of antenatal corticosteroids prior to preterm birth in four South East Asian countries within the SEA-ORCHID project. BMC Pregnancy Childbirth. 2008;8:47.
28. Kamath BD, Macguire ER, McClure EM, Goldenberg RL, Jobe AH. Neonatal mortality from respiratory distress syndrome: lessons for low-resource countries. Pediatrics. 2011;127:1139–46.
29. Carlo WA, Goudar SS, Jehan I, Chomba E, Tshefu A, Garces A, et al. High mortality rates for very low birth weight infants in developing countries despite training. Pediatrics. 2010;126: e1072–80.
30. American Academy of Pediatrics Committee on Fetus and Newborn. Levels of neonatal care. Pediatrics. 2012;130:587–97.
31. Mussi-Pinhata M, Nascimento SD. Neonatal nosocomial infections. J Pediatr. 2001;77:S81-96.
32. Sasidharan K, Dutta S, Narang A. Validity of new ballard score until 7th day of postnatal life in moderately preterm neonates. Arch Dis Child Fetal Neonatal Ed. 2009; 94: F39-44.
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Accepted 2016-08-18
Published 2016-07-01
