Electrocardiographic Pattern in Children suffering from Diphtheria during 1973 at Dr. Cipto Mangunkusumo Hospital, Jakarta

  • Maemunah Affandi Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Bambang Madiyono Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Otty W. Sonityo Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Purwana K. G. Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
DOI: https://doi.org/10.14238/pi16.3-4.1976.81-8
Keywords: electrocardiographic pattern; diphtheria; ecg; AV block

Abstract

ECG abnormalities were found in 39 (45.3%) out of 86 diphtheria cases; 29 cases (33.6%) had significant myocardial involvement. Myocardial involvement comprised minor changes in 24 cases and major changes in 5 cases. Twenty two cases of myocardial involvement occurred in the first week of hospitalization, while 7 cases occurred after the first week of hospitalization. The ECG abnormalities of the 29 cases disappeared within 1 to 2 weeks or after 3 weeks. Minor changes have a good prognosis, while major changes, especially an AV block, have a poor prognosis.

References

1. ALTSCHULLER, S.S.; HOFFMAN, K.M.; and FITZGERAL, P.J.: Electrocardlographic changes in diphtheric.
Ann. Intern. Med. 29 : 294 (1948).
2. ARYANPUR, L.; RAAFAT, F .; AGHIGHIE, Y,; RECIDE, P. and MOAZAMI, R. : Prognosis of diphtheric myocarditis with block. Intern. Cong. Pediatr. XII proceedings 4 : 26 (1971).
3. ASRIL AMINULLAH; MAEMUNAH B. AFFANDI; A. HANAFIAH and SUTEDJO : A 3year clinical evaluation
of diphtheria. Pediatr. Indones. 9 : 171 (1969).
4. BAMBANG MADYONO; MAEMUNAH B. AFFANDI and SUTOTO: Electrocardiographic evaluation dengue hemorrhagic fever. Presented at 1he 3rd Indonesian National Congress of Pediatrics (KONIKA III); Surabaya, July 1- 7, 1974.
5. BEGG, N.D. : Diphtheritic myocarditis; an electrocardiographic study. Lancet 1 : 856 ( 1937).
6. BOYER, N.H. and WEINSTEIN, L. : Diphtheritic myocarditis. New Engl. J. Med. 239 : 913 (1948).
7. GORE, I. : Myocardial changes in fatal diphtheria. Amer. J. Med. Sci. 215 : 157 (1948).
8. JAMES, T.N. and REYNOLDS, E .W. : Pathology of the cardiac conduction system in case of diphtheria associated with atrial arrhytmia and heart block. Circulation 28 : 263 (1963).
9. KEITH, J .D.; ROWE, R.D. and VLAD, P. : Heart disease in infancy and childhood. 2nd ed. (Macmillan, London 1967).
10. KWARI SATJADIBRATA; YAP KHEE NIO; and THE SOEY LIANG : A clinical study of diphtheria with special reference to cardiac compllcation.
Pediatr. Indones. 5 : 928 (1965).
11. KROVETZ, L.J.; GESSNER, I.H. and SCHIBLER, A.F.: Handbook of pediatric cardiology (Harper & Row,
New York 1969).
12. LEDBETTER, M.K.; CANNON, A.B. and COSTA, A.F.: The electrocardiogram in diphtheritic myocarditis.
Amer. Heart J. 68 : 599 (1964).
13. MAEMUNAH B. AFFANDI; KARJOMANGGOLO, W.T.; RANTI, I.S.F. and WIDODO TALOGO, R.: Diphtheria in childhood in Djakarta, Pediatr. Indones. 5 : 942 (1965).
14. MORGAN, B.C. : Cardiac complication of diphtheria. Pediatrics 32 : 549 (1963) .
15. MORALES, A.R.; VICHITBANDA, P.; CHANDRUANG, P.; EVANS, H., and BOURGEOIS, H.C. : Pathological
features of cardiac conduction disturbamces in diphtheritic myocard~tis. Ach. Path. 91 : 1 (1871).
16. NADAS, A.S. : Pediatrics cardiology. 2nd ed. (Saunders, Philadelphia 1968).
17. NELSON; VAUGHAN and McKAY: The textbook of pediatrics. 9th ed. (Saunders, Philadelphia 1969).
18. SIDARTHA, H. and TAGOR, G.M. : The incidence of cardiac involvement in diphtheria. Asian J. Med. 9 : 200 (1973) .
19. TAHERNIA, A.C. : Electrocardiographic abnormalities and serum transaminase levels in diphtheritic
myocarditis. J . Pediatr. 75 : 1008 (1969).
20. WITTELS, B. and BRESSLER, R. : Biochemical lesion of diphltheria toxiat in the heart. J. Clin. Invest. 43 : 630 (1964) .
Published
2019-09-13
How to Cite
1.
Affandi M, Madiyono B, Sonityo O, G. P. Electrocardiographic Pattern in Children suffering from Diphtheria during 1973 at Dr. Cipto Mangunkusumo Hospital, Jakarta. PI [Internet]. 13Sep.2019 [cited 19Apr.2024];16(3-4):81-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2299
Issue
Vol 16 No 3-4 (1976): March - April 1976
Section
Pediatric Cardiology

Copyright (c) 2019 Maemunah Affandi, Bambang Madiyono, Otty W. Sonityo, Purwana K. G.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Received 2019-09-13
Published 2019-09-13