Methylprednisolone as an alternative therapy for Kawasaki disease: case series

Main Article Content

Yudha Fadhol Arafah
Sasmito Nugroho
Noormanto Noormanto
Nadya Arafuri
Indah Kartika Murni

Abstract

Kawasaki disease (KD), or mucocutaneous syndrome, is an acute, systemic vasculitis of small- and medium-sized arteries that predominantly affects patients younger than five years.1  KD is the leading cause of childhood acquired heart disease in the developed world.2 The incidence in those aged under 5 years varies widely throughout the world, accounting for 8.4 per 100,000 in the UK, 17.5 to 20.8 per 100,000 in the USA, and 239.6 per 100,000 in Japan.2


The diagnosis of classic KD is based on the simultaneous presence of high fever for 5 or more days with at least four of five other symptoms (bilateral conjunctival hyperemia, ulcerations of the lips and inflammation of the oral cavity, polymorphous rash, edema and desquamation of the extremities, and cervical lymphadenopathy), or fever associated with less than 4 of the diagnostic criteria and echocardiographic abnormalities of the coronary arteries.3

Article Details

How to Cite
1.
Arafah Y, Nugroho S, Noormanto N, Arafuri N, Murni I. Methylprednisolone as an alternative therapy for Kawasaki disease: case series. PI [Internet]. 14Aug.2020 [cited 27Oct.2020];60(5):283-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2172
Section
Case Report
Author Biographies

Sasmito Nugroho

Department of Child Health, Universitas Gadjah Mada Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java

Noormanto Noormanto

Department of Child Health, Universitas Gadjah Mada Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java

Nadya Arafuri

Department of Child Health, Universitas Gadjah Mada Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java

Indah Kartika Murni

Department of Child Health, Universitas Gadjah Mada Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java

Received 2019-03-30
Accepted 2020-08-14
Published 2020-08-14

References

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