Uric acid and blood pressures in low birth weight 7-year-olds
Abstract
Background Low birth weight (LBW) has been associated withincreased cardiovascular diseases, including hypertension, during
adulthood. Nephrogenesis impairment in LBW may lead to an
increase of uric acid and hypertension.
Objective To assess for a correlation between uric acid and blood
pressures in LBW children.
Methods This study was conducted from January to April 20 12.
A comparative and correlative analytic-observational study with a
cross-sectional method was done in children aged 7-8 years, born
at Prof. Dr. RD Kandou General Hospital and living in Manado.
Forty-eight LBW children and 48 normal birth weight (NBW)
children were included in this study. All children underwent uric
acid level and blood pressures measurements.
Results Mean uric acid level in LBW children was significantly
higher than in NBW children (P = 0.001) . There was no correlation
between uric acid and blood pressures in LBW children(r=0.13,
P> 0.05 for systolic blood pressure; r=0.05, P> 0.05 for diastolic
blood pressure).
Conclusioru; LBW children have higher uric acid levels than
NBW children, but no correlation is found between uric acid level
and blood pressures.
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Accepted 2016-08-17
Published 2014-04-30
