Acute Non Lymphoblastic Leukemia in the Department of Child Health School of Medicine, University of North Sumatera/ Dr. Pirngadi Hospital Medan (1983-1988): A Preliminary Study

  • Feraluna Nasution Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
  • Zairul Arifin Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
  • Adi Sutjipto Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
DOI: https://doi.org/10.14238/pi31.9-10.1991.268-72
Keywords: acute non lymphoblastic leukemia; leukemia; ANLL; FAB classification; cytostatics

Abstract

A retrospective study on Acute Non Lymphoblastic Leukemia (ANLL) was conducted at the Sub Division of Pediatric Hematology, School of Medicine, University of North Sumatera/Dr. Pirngadi Hospital Medan, in a period of 5 years (1983-1988).

There were 18 cases consisted of 14 (77. 78%) males and 4 (22 .22%) females with the age group of 0-2 years: 6 (30%), 2-8 years: 9 (50%), 8-15 years: 3 (30%). By the FAB classification, they were of FAB M-1: 1 (5.55%), FAB M-2: 1 (5.55%), FAB M-3: 1 (5.55%), FAB M-4: 2 (11.12%) and FAB M-6: 13 (72.23%). Only 7 (38.88%) were treated with cytostatics while the others received only supportive therapy. The result of  cytostatic treatment was unsatisfactory: 4 (57.14%) died within the first 2 months of treatment, 3 (42.86%) discontinued their cytostatics treatment.

References

1. CREUTZIG U, RITTERJ, RIEHM H, BUDDE M, SCHELLONG G. The Childhood AML. Studies BFM-78 and -83: Treatment Results and Risk Factor Analysis; in BUCHNER, SCHELLONG, HIDDEMANN, URBANITZ, RITTER, eds, Haematology and Blood Transfusion, Berlin, Heidelberg: Springer-Verlag, 1987: 71-S.
2. KOBRINSKY, N.L.; ROBISON, L.L.; NESBIT, M.E.: Acute Nonlymphocytic Leukemia. In the Pediatric Clinics of North America. Altman, A.J.
3. LEVENTHAL BG. Neoplasm and Neoplasm. Nelson Text Book of Pediatrics 13th ed, Philadelphia: WB Saunders, 1987: 1079-110.
4. HERMANN J, PLENERT W! ZINTL F, et al. Improved Treatment Result in Childhood Non Lymphoblastic Leukemia with the BFMAML Protocol 78 in a Multicenter Study in the GDR; in BUCHNER, SCHELLONG, HIDDEMANN, URBANITZ, RITTER, eds, Haematology and Blood Transfusion, Berlin, Heidelberg: Springer-Verlag, 1987: 76-82.
S. WEINSTEIN H, GRIER H, GELBER R, CAMITTA B, LINK M, DELOREY M, PRICE K. Psotremission Induction Intensive Sequential Chemotherapy for Children with AML – Treatment Results and Prognostic Factors; in BUCHNER, SCHELLONG, HIDDEMANN, URBANITZ, RITTER, eds, Haematology and Blood Transfusion, Berlin, Heidelberg: SpringerVerlag, 1987: 88-92.
Published
2019-02-01
How to Cite
1.
Nasution F, Arifin Z, Sutjipto A. Acute Non Lymphoblastic Leukemia in the Department of Child Health School of Medicine, University of North Sumatera/ Dr. Pirngadi Hospital Medan (1983-1988): A Preliminary Study. PI [Internet]. 1Feb.2019 [cited 13Nov.2024];31(9-10):268-2. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2131
Issue
Vol 31 No 9-10 (1991): September - October 1991
Section
Pediatric Hemato-Oncology

Copyright (c) 2019 Feraluna Nasution, Zairul Arifin, Adi Sutjipto

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Received 2019-02-01
Published 2019-02-01