The Pattern of Thalassemia in Children at the Department of Child Health, School of Medicine University of North Sumatera/ Dr. Pirngadi Hospital, Medan

  • Sugiani Sinulingga Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
  • Ismet Fadil Loebis Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
  • Adi Sutjipto Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
DOI: https://doi.org/10.14238/pi31.9-10.1991.261-7
Keywords: thalassemia; anemia; hepatomegaly; hepatosplenomegaly

Abstract

A study of the characteristics of childhood thalassemia was conducted at the Sub Department of Pediatric Hematology, Dr. Pirngadi Hospital from June 1979 to May 1989.

There were 131 cases, consisting of75 (57.25%) boys and 56 (42.75%) girls with an average of 12 admission every year. The predominant age group was 0-2 years, and the youngest was 3 months old; Javanese ethnic group appeared predominant in 36 (63.15%) cases.

Clinical symptoms of anemia were found in 112 (85.49%}, hepatomegaly in 91 (69.46%}, hepatosplenomegaly in 84 (64.12%}, without enlargement of organ in 17 (12.97%), and icterus in 6 (4.58%). Hb-Electrophoresis was done in 42 cases, revealing 26 (61.90%) with thalassemia major, 15 (35.71%) Hb E thalassemia, and 1 (2.20%) Hb H thalassemia. Hb value at the first admission in 65 (49.62%) was less than 5 g/dl, in 63 (48.09o/o) it was 5-10 g/dl and in 3 (2.29%) more than 10 g/dl.

References

1. NIENHUIS AW. Propper PD. The Thalassemia In: Nathan DG, eds. Hematology of infancy and childhood. Philadelphia : WB Saunders, 1975: 726-787.
2. PERASON HA. Thalasemia. In: Behrman RE, eds. Nelson Textbook of pediatrics. Philadelphia: WB Saunders, 1987: 1052-1054.
3. GITHAUS JH, HATHAWAY EW. Hematology disorder. In: Kempe, eds. Current pediatric diagnosis and treatment : Prentice-Hall International, 1987: 474-477.
4. ISKANDAR W. Thalassaemia. Jakarta, University of Indonesia, 1979. Disertation.
Published
2019-02-01
How to Cite
1.
Sinulingga S, Loebis I, Sutjipto A. The Pattern of Thalassemia in Children at the Department of Child Health, School of Medicine University of North Sumatera/ Dr. Pirngadi Hospital, Medan. PI [Internet]. 1Feb.2019 [cited 20Apr.2024];31(9-10):261-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2130
Issue
Vol 31 No 9-10 (1991): September - October 1991
Section
Pediatric Hemato-Oncology

Copyright (c) 2019 Sugiani Sinulingga, Ismet Fadil Loebis, Adi Sutjipto

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Received 2019-02-01
Published 2019-02-01