A Study of Aplastic Anemia at the Department of Child Health, School of Medicine University of North Sumatera/Dr. Pirngadi Hospital, Medan

  • Ajuar Arif Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
  • Adi Sutjipto Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North Sumatera
Keywords: aplastic anemia; paleness; fever; bleeding; thrombocytopenia

Abstract

A study of aplastic anemia in children in a period of June 1980 to June 1989 was done to evaluate the pattern of aplastic anemia in children. The cases consisted of 55 children, 30 males (54.55%) and 25 females (45.45%). Most of the patients (47.27%) were found in the age group of 10 to 15 years. The complaints were paleness (90.91%), fever (56.45%) and bleeding (52. 71%). The hemoglobin concentration was 4.25 ± 1.17 g/dl (mean ± SD), and the thrombocytopenia was generally severe.

Prednisone or combination of prednisone and oxymethalone was given in addition to blood transfusions, antibiotics and vitamins. The outcome was difficult to evaluate because of the irregularity of treatments. Of the 55 children, 9 (18.02%) contracted leukemia after 1 - 5 months.

References

1. ALTER B P, RAPOPORT J M, PARKMAN R. The bone marrow failue syndromes; in Nathan, D.O.: Hematology of infancy and childhood; 2nd ed. Philadelphia : WB Saunders, 1981: 169-96.
2. WINTROBE MM. Pancytopenia aplastic anaemia and "Pure red cell" aplastic; in Wintrobe, M.M.: Clinical hematology; 7th ed. Philadelphia: Lea & Febiger, 1974 : 1741-71.
3. UNTARIO S, TANTRI YUWANA, SUNARWAN. Aplastic anaemia. Paediatr lndones. 1970; 10: 7-17.
4. ERSLAN AJ. Aptastic anaemia; in William, J.W. et al.: Hematology; 2nd. ed. New York: McGrow-Hill Book, A Blakiston Publication, 1977: 258-73.
5. MARKUM AH, WAHIDIYAT I, ABDULSALAM M, ODANG 0, MUSLICHAN S. Clinical and hematologic pictures of preleukemia stage. Pediatr. lndones. 19721tJ12 : 489-98 .
6; CHOUNDRY VP, ADHIKARl RK. Aplastic anaemia an early phase preceeding acute lymphatic leukemia. Indian J . Pediatr. 1982; 49: 343-7.
Published
2019-01-31
How to Cite
1.
Arif A, Sutjipto A. A Study of Aplastic Anemia at the Department of Child Health, School of Medicine University of North Sumatera/Dr. Pirngadi Hospital, Medan. PI [Internet]. 31Jan.2019 [cited 25Apr.2024];31(9-10):253-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2129
Section
Pediatric Hemato-Oncology
Received 2019-01-31
Published 2019-01-31