Steatocrit: A Simple Method for Detection Fat Malabsorption

  • Suharyono Suharyono Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Hindra Irawan Satari Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Agus Firmansyah Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Keywords: steatocrit; fat malabsoprtion; lipiodol absorption test

Abstract

Steatocrlt was determined through microcentrifugation of fecal hemogenate from 45 patients with chronic diarrhoea. In the same patients urine materials were collected to determine fat malabsorption using Lipiodol absorption test. There were 28 male and 17 female patients. Severe malabsorption using steatocrit was detected tn 31 patients (68;9%), while LAT determined severe malabsorption in 34 patients (75.5%). The overall sensitivity was 88.2%, and spesificity was 90.9%. Nutritional status did not influence the sensitivity and spesificity of steatocrit. We propose that this simple semiquantitative test can be used as an alternative method for detecting fat malabsorption particularly in laboratories with limited technical expertise.

References

01. Lebenthal E. Prolonged small intestine mucosal injury as a primary cause of intractable diarrhea of infancy; in lebenthal, chronic diarrhea in children; 1st ed., New York : Reven Press 1984; 5 - 30.
02. Galli C. Absorption, metabolism and utilization of fat during development. Annales Nestle. Special edition (1984).
03. Kamer JH, Bokel Huinink H, Weyers HA. Rapid method for the determination of fat in feces. J bioi Chern 1977: 343- 55 (1949).
04. Drummey BS, Menson JA, Jones CM. Microscopical examinations on the stool for steatorrhoea. New Engl J Med 1961; 61 : 264.
05. Jones WO, di Sant'Agnese PA. Laboratory aids in the diagnosis of malabsorption in pediatrics: Lipiodol absorption test as a simple test for steatorrhea. J Pediatr 1963; 62 : 44 - 9.
06. Suharyono, Sunoto, Aswitha B, Hentyanto H. Malabsorption syndrom in Indonesia children. Presented at the Vth World Congress of Gastroenterology, Mexico 1974.
07. Phuapradit P, Narang A, Mendonca P, Harris DA, Baurn JD. The steatocrit : a simple method for estimating stool fat content in newborn infants . Arch Dis Child 1981; 56 : 725 - 7.
08. Colombo C, Maiavacca R, Ronchi M, Consalvo E, Arnoretti M, Guinta A. The steatocrit : A simple method for monitoring fat malabsorption in patients with cystic fibrosis. J Pediatr Gastroenterol Nutr. 1987; 6 : 926 - 30.
09. D'Agostino, Orsi M. The steatocrit (letter to editor). J Pediatr Gastroenterol Nutr 1988; 7 : 935 - 6.
10. Carrocio A, Pardo F, Montalto G, Japichino L, Lacono G, Collura M, Notarbartolo A. Effectiveness of entericcoated preparations on nutritional parameters in cystic fibrosis. A long-term study. Digestion 1988; 41 : 201 - 6.
11. Patane R, Bottaro G, Ricca 0, Cagnina M, Failla P, Ciulla U, Opinto V, Di Pietro MC, Castiglione N. Qualitative test of fecal fat and steatocrit, simple complementary methods for the evaluation of steatorrhea in childood. Pediatr Med Chir 1988; 10 : 403 - 8.
12. Iacono G, Carrocio A, Cavataio F, Montalto G,Mancuso C, Balsamo V, Notarbartolo A. Steatocrit test : normal range and physiological variations in infants. J Pediatr Gastroenterol Nutr 1990; 11 :53-7.
Published
2019-01-30
How to Cite
1.
Suharyono S, Satari H, Firmansyah A. Steatocrit: A Simple Method for Detection Fat Malabsorption. PI [Internet]. 30Jan.2019 [cited 13Nov.2024];32(11-12):298-03. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2121
Section
Pediatric Gastrohepatology
Received 2019-01-30
Published 2019-01-30