Evaluation of Cardiac Involvement by Echocardiography in Children with Acute Meningococcemia

  • Semra Atalay Department of Cardiac Dr. Sami Ulus Children's Hospital, Ankara, Torkiye
  • Hulya Kahraman Department of Cardiac Dr. Sami Ulus Children's Hospital, Ankara, Torkiye
  • Saimin Karademir Department of Cardiac Dr. Sami Ulus Children's Hospital, Ankara, Torkiye
  • Musa Kazim Caglar Department of Cardiac Dr. Sami Ulus Children's Hospital, Ankara, Torkiye
Keywords: acute meningococcemia; myocarditis; endotoxemia; echocardiographic

Abstract

Myocarditis in acute meningococcemia is rare in children. Impaired cardiac contractile function may contribute to cardiovascular collapse in endotoxemia. We evaluated prospectively the clinical and echocardiographic findings in 25 consecutive children with acute meningococcemia. All of the patients had good prognostic indicators. Eleven (44%) of the 25 children bad echocardiographic evidence of myocardial dysfunction. The mean LVFS in these eleven children was 0.23 ± 6.00, as compared with the mean LVFS of0.34±8.87 in the remaining children. LVFS returned to normal within 7 days in all patients. We observed minimal pericardia/effusion in 4 patients (16%) that resolved within 3 days. We demonstrated that acute meningococcemia is frequently associated with myocardial dysfunction. We could not though, find the relation between myocardial dysfunction and mortality.

References

1. Powell KR. Meningococcemia. In : Hoekelman RA, Blatman S, Friedman SB, Nelson NM and Seidel HM (eds) Primary Pediatric Care. The CV Mosby Company, St Lo uis, Washington DC, Toronto, 1987, pp. 1613-16 .
2. Steihm RE, Darruosch DS. Factors in the prognosis of meningococcal infection. ] Pediatr 68 : 457; 1966.
3. Cahalane SP, Waters M. Fulminant meningococcal septicaemia. Lancet 2: 120; 1975 .
4. Hardman]M, Earle KM. Myocarditis in 200 fatal meningococcic infections. Arch Pathol 87 : 318; 1969.
5. Saphlr 0. Meningococcus myocarditis. Am J Pathol 12: 677; 1936.
6. Rao PS, Dahm CH, Riner HA, ]o AB, Bhagat B. lmpairement of myocardial performance in endotoxic shock. J Moll Cell Cardiol 10 (Suppl 1) : 86; 1987. 7. Parker JJ, Adams HR. Development of myocardial dysfunction in endotoxic shock. Am] Physiol248: 818; 1985.
8. Lefer AM. Role of carticosteroids in the treatment, of circulatory collapse states. Clin Pharmacol Ther 11 : 630; 1970.
9. Boucek MM, Boerth RC, Arunan M, Graham TP, Boucek RJ. Myocardial dysfunction in children with acute meningococcemia. J Pediatr 1 05 : 538; 1984 .
10. Parker MM, Shelhamer JH, Bacharach L, Green MY, Natanson C, Frederic TM, Darnsake BA, Parrillo }E. Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med 100 : 483; 1984.
11. Scon LP, Knox D, Perry LW, Pineros-Torres FJ. Meningococcal pericarditis. AM ] Cardiol 29 : 104; 1972.
12. Boyle JD, Pearce ML, Guze LB. Purulent pericarditis : Review of literature and report of eleven cases. Medicine 40: 119; 1961
13. Morse JR, Oretsky MI, Hudson JA. Pericarditis as a complication of meningococcal meningitidis. AM Intern Med74: 212; 1971 .
14. Nichols DA, Peter RH. Constrictive pericarditis as a late complication of meningococcal pericarditis. Am J Cardiol. 55:1442; 1985.
15. Losekoot JG, Becker AE. Non-rheumatic inflammatiory heart disease in: Anderson RH, Macartney FJ, Shinebourne EA, Tynan M (eds). Paediatric Cardiology (1st ed), Churchil livingstone, New York, Volume II, 1987: pp. 1165-77.
16. lkaheimo MJ, Takkunen JT. Echocardiography in acute infectious myocarditis. Chest 89 : 100; 1986.
17. Hauser AM, Gordon S, Cieszkowski J, Tirnmis GC. Severe transient left ventricular "hypertrophy" occuring during acute myocarditis. Chest 83 : 275; 1983.
18. Oda T, Hamamoto K, Morinaga H. Left ventricular hypertrophy in nonrheumatic myocarditis in children. Jap Circ J 46 ; 1235; 1982 .
19. Blaser MJ, Reingold AL, Alsever RN and Hightower A. Primary meningococcal pericarditis : A disease of adult association with serogroup C Neisseria meningitidis. Reviews of Infectious Disease 6: 625; 1984.
Published
2018-12-11
How to Cite
1.
Atalay S, Kahraman H, Karademir S, Caglar M. Evaluation of Cardiac Involvement by Echocardiography in Children with Acute Meningococcemia. PI [Internet]. 11Dec.2018 [cited 22Nov.2024];33(1-2):9-4. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2049
Section
Pediatric Cardiology
Received 2018-12-10
Published 2018-12-11