HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers

  • Adnan S. Wiharta Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Evi Setiadi Department of Biochemistry, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • H. M. Sjaifullah Noer Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Triyatmo Rachimhadhi Department of Obstetrics & Gynaecology, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Asri Rasad Department of Biochemistry, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
DOI: https://doi.org/10.14238/pi34.5-6.1994.125-8
Keywords: HBsAg; cord bloos; HBsAg positive; vertical transmission; hepatitis B

Abstract

Vertical transmission of hepatitis B infection that may occur during pregnancy at delivery-, in infancy, and early childhood has an important role in the development of chronic hepatitis B. Intrauterine infection is suspected to occur when hepatitis B viruses cross the placenta into fetal circulation due to failure of placental tissue function. In Cipto Mangunkusumo Hospital, Jakarta, 98 (6.4%) of 1536 pregnant mothers obseiVed during 3 years (1987 -1990) showed positive HBsAg. Six (8.3%) of 60 babies of born to HBsAg positive mothers showed positive HBsAg in their cord blood, but this disappeared after one month. All babies born to HBsAg positive mothers were vaccinated on months 0, 1, 2, and 12. HBsAg in cord blood might not play an important role in vertical transmission.

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Published
2018-11-05
How to Cite
1.
Wiharta A, Setiadi E, Noer HM, Rachimhadhi T, Rasad A. HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers. PI [Internet]. 5Nov.2018 [cited 2May2024];34(5-6):125-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2020
Issue
Vol 34 No 5-6 (1994): May - June 1994
Section
Neonatology

Copyright (c) 2018 Adnan S. Wiharta, Evi Setiadi, H. M. Sjaifullah Noer, Triyatmo Rachimhadhi, Asri Rasad

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Received 2018-11-05
Published 2018-11-05