Primary Hyperparathyroidism Caused by Single Parathyroid Adenoma
Abstract
Primary hyperparathyroidism is rarely found in children under sixteen years old. We report the first case seen at the Department of Child Health, Medical School, University of Indonesia, Jakarta. This 15-year old girl was admitted to the Department, referred by an orthopedic surgeon because of pathologic fractures suspected to be caused by hyperparathyroidism. The physical examination was unremarkable, and the laboratory findings showed increased level of parathyroid hormone. Roentgenologic examination showed lytic skull lesions, loss of the lamina dura of the dentis, subperiosteal resorption of the symphysis and generalized osteoporosis with pathologic fractures. Color Doppler USG using a high resolution ultrasound examination was performed to find the etiology of primary hyperparathyroidism. The result revealed single parathyroid adenoma in the right superior region measuring 2.7 x 1.7 x 1 cm. The clinical manifestation and laboratory findings showed improvement following surgery.
References
2. Rappaport D, Ziv Y, Rubin M, Huminer D, Dintsman M. Primary hyperparathyroidism in children. J Pediatr Surg 1986; 21:395-7.
3 Netter FH Forsham PH. Endocrine system and selected metabolic diseases. The CIBA collection of medical illustrations. Volume 4. CIBA 1965:177-83.
4 Heath III H, Hodgson SF, Kennedy MA. Primary hyperparathyroidism. Incidence, morbidity, and potential economic impact in a community. N Engl J Med 1980;302:189-93.
5. Nolan RB, Hayles AB, Woolner LB. Adenoma of the parathyrotd gland in children. Report of case and brief review of the the literature. Am J Dis Child 1960,99. 622-7.
6. Hindie E, Melliere D, Simon D, Perlemuter, Gallel P. Primary hyperparathyroidism: Is Technetium 99m-Sestamibi/Iodine-123 subxtraction scanning the best procedure to locate the enlarged glands before surgery. J. Clin Endocrinol. Metabol 1995;80:302-7.
7. Mitchell BK, Kinder BK, Cornelius E, Stewart AF. Primary hyperparathyroidism: preoperative localization using Technetium-Sestamibi scanning. J Clin Endocrinol Metabol. 1995;80:7- 10.
Copyright (c) 2018 Jose R. L. Batubara, Paruhum T. Siregar, M. Lutfi, Daniel Makes, Wawan Hermawan
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Published 2018-10-08