Congenital Toxoplasmosis in a 15 Day-Old Infant a Case Report

Sri Rezeki Harun; Evita K. Saleh; Srisasi Gandahusada; Chairil Hamdani

doi:10.14238/pi29.7-8.1989.151-9

Sri Rezeki Harun Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Evita K. Saleh Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Srisasi Gandahusada Department of Parasitology, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Chairil Hamdani Department of Pathology, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta

DOI: https://doi.org/10.14238/pi29.7-8.1989.151-9

Keywords: congenital toxoplasmosis; toxoplasma gondii; hydrocephalus; cerebral calcification; chorioretinitis

Abstract

A case of congenital toxoplasmosis in a 1 5-day old infant was reported, citing the difficulties encountered in establishing the diagnosis due to the wide range of the disease's clinical spectrum. Congenital toxoplasmosis was suspected after finding hydrocephalus, cerebral calcification, and chorioretinitis. Serology tests with the ELISA technique were highly positive for antibodies against lgG, whereas anti-IgM was negative. The patient died before the second serological analysis was done. The final diagnosis of congenital toxoplasmosis was eventually established at autopsy, based on the detection of T. gondii in the brain, testicular, liver, spleen and striated muscle tissues.

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