Effect of Vitamin A supplementation on the Serum levels of some Immunoglobulin in Vitamin A deficient children

  • S. M. Faruque Department of Biochemistry University of Dhaka Dhaka-2, Bangladesh
  • Yearul Kabir Department of Biochemistry University of Dhaka Dhaka-2, Bangladesh
  • S. A. M. Khairul Bashar Department of Biochemistry University of Dhaka Dhaka-2, Bangladesh
Keywords: vitamin A; supplementation; immunoglobulis; IgG, IgA; IgM; vitamin A deficiency

Abstract

Effect of vitamin A deficiency and of subsequent vitamin A supplementation on the serum levels of immunoglobulins, lgG, lgA and lgM were studied in children with severe to moderate vitamin A deficiency. Decreased levels of lgG ( P < 0. 001 ), lgA ( P < 0.01 ) and increased levels of serum lgM ( P < 0.01 ) were found in vitamin A deficient children, compared to normal. On supplementation of 100,000-200,000 iu. Of vitamin A, during a period of 2 weeks, serum lgG, IgA and IgM levels in the vitamin A deficient children increased by 49.4 ± 7.2%, 14.2 ± 7. 7%, and 8.0 ± 2.3% respectively with an increase in the serum vitamin A levels by 4 7. 6 ± 10. 6 per cent. The results have been discussed on the possible interactions of vitamin A deficiency and immunity.

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Published
2018-08-10
How to Cite
1.
Faruque S, Kabir Y, Bashar SAM. Effect of Vitamin A supplementation on the Serum levels of some Immunoglobulin in Vitamin A deficient children. PI [Internet]. 10Aug.2018 [cited 2May2024];24(11-12):249-3. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1933
Section
Pediatric Nutrition & Metabolic Disease
Received 2018-08-10
Published 2018-08-10