Hepatitis C in A Child with Thalassemia

  • Dina Dina Department of Child Health, Udayana University Medical School/Sanglah Hospital, Denpasar, Bali Dina, Anky Tri Rini, M. Widia, Sudaryat S
  • Anky Tri Rini Department of Child Health, Udayana University Medical School/Sanglah Hospital, Denpasar, Bali
  • M. Widia Department of Child Health, Udayana University Medical School/Sanglah Hospital, Denpasar, Bali
  • Sudaryat S. Department of Child Health, Udayana University Medical School/Sanglah Hospital, Denpasar, Bali
Keywords: hepatitis C, thalassemia, thalassemia major

Abstract

We present a case of hepatitis C in a patient with thalassemia major. The transmission seems to be through blood transfusion. The diagnosis of hepatitis C was determined by the presence of anti HCV in serum. Ursodeoxycholic acid therapy gave a satisfactory result and the patient was discharged after showing improvement of both clinical signs and liver function tests. He was suggested for regular examination to evaluate anti HCV and his thalassemia. lt is believed that if anti HCV titer is more than 6 months, hepatitis may become chronic hepatitis C.

References

1. Alter HJ. Detection of antibody to hepatitis C virus prospectively followed transfusion recipients with acute and chronic non a - non b hepatitis. New Engl J Med. 1989; 321: 494-500.
2. Mowat AP. Liver disorder in childhood. 2nd ed. London: Butterworth; 1987. p. 106.
3. Sherlock S. Disease of the liver and billiary system. Blackwell Scientific Publications, USA, 4th ed. 1989: 365-7.
4. Timan IS. Diagnosis laboratorik hepatitis C. Hepatologi anak masa kini. FKUI: Jakarta; 1992. p. 149-53.
5. Alter HJ. Importance of heterosexual activity in transmission of hepatitis b and non-a, non-b hepatitis. JAMA. 1989; 262: 1201-5.
6. Novak DA. Disorder of the liver and biliary system relevant to clinical practice. In Oski FA, EDS. Principles and practice of pediatrics. 2nd ed. Philadelphia: J B Lippincott Co.; 1990. p. 1762-9.
7. Weijstal R. Mother to infant transmission of hepatitis c virus infection. Virology J Med. 1990; 30: 178-80.
8. Weiner AJ. Detection of hepatitis c viral sequences in non-A, non-B hepatitis. Lancet. 1990; 335: 1 - 3.
9. Wiharta AS, Timan IS. Hepatitis C pada penderita talasemia. Hepatologi Anak Masa Kini. Jakarta: FKUI;1992. p. 163-9.
10. Wiharta AS. Hati dan Saluran Empedu, Buku Ajar Ilmu Kesehatan Anak. Jakarta: FKUI; 1991. p. 523-7.
11 . Wikanta M, Rustam M. Survei prevalensi hepatitis c diantara donor darah sukarela di Jawa dan Bali. Hepatologi anak masa kini. Jakarta: FKUI; 1992. p. 129-35.
12. Hidayat B. Hepatitis C pada anak. Hepatologi Anak Masa Kini. Jakarta: FKUI; 1992. p. 137-46.
13. Poel vd CL, Reesink HW, Schaasberg W. Infectivity of blood seropositive for hepatitis C virus antibody. Lancet. 1990; 335: 558-60.
14. Soewignjo Soemohardjo. Terapi hepatitis kronik dengan interferon alfa. Round Table Discussion Terapi Interferon Alfa pada Hepatitis Kronik. Denpasar: RSUP Sanglah Denpasar; 1992. p. 12-20.
15. Balart LA. Treatment of chronic hepatitis C with combinant interferon alfa. N Engl J Med. 1989; 321:1501-6.
16. Sulaiman A. Pengobatan hepatitis C Kronik dengan interferon. Hepatologi Anak Masa Kini. Jakarta: FKUI; 1992. p. 155-61.
Published
1995-02-27
How to Cite
1.
Dina D, Rini A, Widia M, S. S. Hepatitis C in A Child with Thalassemia. PI [Internet]. 27Feb.1995 [cited 23Nov.2024];35(1-2):47-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1823
Received 2018-03-23
Accepted 2018-03-23
Published 1995-02-27