Thyroxine Levels in the Nephrotic Syndrome

  • Ariyanto Harsono Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java
  • Sardjito Djojohadipringgo Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java
  • I. Nyoman Yardana Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java
Keywords: throxine, nephrotic syndrome, serum albumine, globuline

Abstract

Thirteen children, seven boys and six girls aged between 3 to 12 years wit/1
the diagnosis of Nephrotic Syndrome were assessed for clinical and laboratory
figns with special attention on T 4 levels.


In the first examination, done during the full blown illness, T4 levels ranged
between 1 ug % to 10 ug % (mean: 5.4 + 3.14 ug %).


In remission the levels were significantly elevated, ranges between 3.6 ug % to 18.6 ug% rmean: 11.6 + 5.34 ug %).


Meanwhile, the observation of serum albumine and globuline concentrations showed a significantly rise ( p<0.005).


Comparison with the results of other investigators have also been discussed.

References

1. BURGER, A.; SUTER, P.; NICOD, P.; VALLOTTON, M.B.; : Reduced activo
Thyroid hormone levels in acute illness. Lancet i : 653-655 (1976).
2 . DiGEORGE, A.M. : Thyroid Hormone studies in Nelson's Textbook of Pedia· tries. 10th ed. pp. 1302 . 1303 (lgaku Shoin, Tokyo 1975).
3. GEOLA, F.L.; CHOPRA, I.J .; GEFFNER, D L. : Patterns of 3,3',5'-Triiodo
Thyronine Monodeiodir..ation in Hypothyroidism and Nonthyroid Illnesses. J.
din. Endocr. Metab. 50 : 336 - 340 (1980).
4. KALANT, N.; MciNTYRE, W.C.I. WIJANSKY, D.L. : Thyroid function iq
232 THYROXINE LEVELS IN NEPHROTIC SYNDROME experimental Nephrotic Syndrome. Endocrinology 64 : 333 - 343 (1959).
5. KALK, W.J.; MORLEY, J.E.; COLD, C.H.; MAYERS, A. : Thyroid functiou
tests in patients on regular hemodialysis. Nephron 25 : 173 - 178 (1980).
6. MURRAY, I.P.G.; JOASOOO, A,; PARKIN, J. : Serum Thyroxine Estimation in Assessment of Thyroid function. Med. J. Aust. 1 : 73 - 76 (1971).
7 RANCE, C.P.; ARBUS, G.S; BALFE, J .W.; : Management of the Nephrotic
Syndrome in Children. Pedi,at. Clins. N. Am. 23 : 735 - 750 (1976).
8. RASMUSSENS, H.; RAPP, B. : Thyroxine metabolism in the Nephrotic Syndrome. J. clin. Invest. 35 : 792 - 799 (1956).
9. RECANT, L. : An abnormal in Thyroxine binding in Nephrosis J. clin. Invest. 35 : 730-731 (1956).
10. ROBINS, J.; RALI, JE.; PATERMAN, M.L, : Thyroxine binding by serum and urine proteins in Nephrosis. Qualitative Aspects. J. clin. Invest. 36 : 1333 - 1342 (1957).
11. WILLIAMS, E.S. : Investigation of the Thyroid. Asian Med. News 2 : 9 - 10 (1980).
Published
1982-12-31
How to Cite
1.
Harsono A, Djojohadipringgo S, Yardana I. Thyroxine Levels in the Nephrotic Syndrome. PI [Internet]. 31Dec.1982 [cited 29Mar.2024];22(11-12):227-4. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1639
Section
Pediatric Nephrology
Received 2017-08-29
Accepted 2017-08-29
Published 1982-12-31