Clinical Evaluation of Dibekacin in Urinary Tract Infection in Children

  • Taralan Tambunan Department of Child Health, University of Indonesia Medical School, Jakarta
  • I. G. N. Wila Wirya Department of Child Health, University of Indonesia Medical School, Jakarta
  • Husein Alatas Department of Child Health, University of Indonesia Medical School, Jakarta
DOI: https://doi.org/10.14238/pi22.9-10.1982.171-80
Keywords: dibekacin, urinary tract infection, UTI

Abstract

Fifty selected cuses of urinary tract infection ( UTI) were treated with Dibekacin
with the do~age of 2 mg/kg BW, IM. for seren days. Thirty five cases
classified as simple UT 1 and /lie rest fifteen cases as complicured urinary infection. Thirty one cases were injected once a day and the remaining nineteen patients twice a day.

The .ciinica!, laboratory und microbiological improvement was 84%, 86%
and 62% respectively. Complete improvement was and on 54% cases only. In
the group of simple UTI, no significant different result was found on different
interval time of drug injection. Similar result was also detected in the group of
complicated UTI. The only significant different result was obtained from the
cumparison between simple and complicated urinmy infection when the drug
was given twice a day, either it was separately assessed clinically, latoratory
and microbiologically or combined. Better result was more pronounced in the
group of simple UTI but we had to be cautious to interpret this finding. Single
daily injection could be reconunended to reduce the dscomfort of parenteral
administration.

References

1. FUJII, R. : Studies on dibekacin in pediatric field. J. Japan med. Assoc. 76 : 49 . 53 (1976).
2. UMEZAWA, H.; S. UMEZAWA; T. TSUCHIYA; Y. OKAZAKI : 3·, 4'- Dideoxykanamycin B active against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa. J. Antibiotics 24 : 485 - 487, (1971).
Published
1982-10-30
How to Cite
1.
Tambunan T, Wirya IGN, Alatas H. Clinical Evaluation of Dibekacin in Urinary Tract Infection in Children. PI [Internet]. 30Oct.1982 [cited 6Feb.2025];22(9-10):171-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1631
Issue
Vol 22 No 9-10 (1982): September - October 1982
Section
Pediatric Nephrology

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Received 2017-08-29
Accepted 2017-08-29
Published 1982-10-30