Spasmophilia
Keywords:
spasmophilia, cephalgia, hypocalcemic, calcium
Abstract
Sixty eight cases of spasmophilia were studied, consisting of 44 girls and 24 boys, the age ranging from 7 to 12 years. The most prominent symptom was cephalgia. Other symptoms included cramps, fainting attacks, abdominal pains, myalgia, breathing difficulties, palpitation, precordial pain, tremor and learning problems. Laboratory examination showed that most of them were hypocalcemic with prolonged Qo - Tc interval in electrocardiogram. BEG showed a certain pattern of increased thetha waves with irregular background activities and nonspecific changes. Treatment with calcium showed good clinical results. There seems to be no correlation between clinical improvement of symptoms and EMG findings.References
BERTRANT, L.; SABORET, P. and LETE, E. : La spasmophilic, tetanic chronique constitutionale. Les Cahiers Sandoz, 1966.
BORGSTEDT, A.D.; BRYSON, M.F.; YOUNG, L.W. and FORBES, G.B. : Long term antiepileptic drugs and the development of rickets. J. Pediatr. 81 : 9 (1972).
COLLETI, R.B.; PAN, M.W.; SMITHE, E.W.P. and GENEL, M. : Detection of hypocalcemi in susceptible neonates. N. Engl. J. Med. 290 : 431 (1974).
DENT, C.E.; RICHENS, A. and ROWE, D.J.F. : Osteomalacia with long term anticonvulsant therapy in epilepsy. Br. med. J, 4 : 69 (1970).
DJOHAN SANTO SO and JOS UTAMA : The treatment of spasmophilia with Calcium Sandoz Forte tablets, Maj. Kedok. Indones. 22 : 102 (1972).
FRANK, J.P. and FRIEDBERG, D.Z. : Syncope with prolonged Q-T interval. Am. J. Dis. Child. 130 : 320 (1976).
MEDLINSKY, H.L. : Rickets associated with anticonvulsant medication. Pediatr. 53 : 1 (1974).
ROTH, B. and NEVSIMAL, 0. : EEG study of tetany and spasmophilia. Elec. troenceph. clin. Neurophysiol. 17 : 36 (1964).
RICKENS, A. and ROWE, D.J.F.: Disturbance of calcium metabolism by anticonvulsants. Br. mcd. J. 4 : 202 (1971).
SCHULTE, F.J. and LOHMANN, A. : The electroencephalogram and electromyogram in experimental hypocalcemia. Electroenceph. Clin. Neurophysiol. 14:915 (1962).
SWASH, M. and ROWAN, A.J. : Electroencephalographic Criteria of hypocalcemia and hypercalcemia. Arch. Neurol. 26 : 218 (1972).
BORGSTEDT, A.D.; BRYSON, M.F.; YOUNG, L.W. and FORBES, G.B. : Long term antiepileptic drugs and the development of rickets. J. Pediatr. 81 : 9 (1972).
COLLETI, R.B.; PAN, M.W.; SMITHE, E.W.P. and GENEL, M. : Detection of hypocalcemi in susceptible neonates. N. Engl. J. Med. 290 : 431 (1974).
DENT, C.E.; RICHENS, A. and ROWE, D.J.F. : Osteomalacia with long term anticonvulsant therapy in epilepsy. Br. med. J, 4 : 69 (1970).
DJOHAN SANTO SO and JOS UTAMA : The treatment of spasmophilia with Calcium Sandoz Forte tablets, Maj. Kedok. Indones. 22 : 102 (1972).
FRANK, J.P. and FRIEDBERG, D.Z. : Syncope with prolonged Q-T interval. Am. J. Dis. Child. 130 : 320 (1976).
MEDLINSKY, H.L. : Rickets associated with anticonvulsant medication. Pediatr. 53 : 1 (1974).
ROTH, B. and NEVSIMAL, 0. : EEG study of tetany and spasmophilia. Elec. troenceph. clin. Neurophysiol. 17 : 36 (1964).
RICKENS, A. and ROWE, D.J.F.: Disturbance of calcium metabolism by anticonvulsants. Br. mcd. J. 4 : 202 (1971).
SCHULTE, F.J. and LOHMANN, A. : The electroencephalogram and electromyogram in experimental hypocalcemia. Electroenceph. Clin. Neurophysiol. 14:915 (1962).
SWASH, M. and ROWAN, A.J. : Electroencephalographic Criteria of hypocalcemia and hypercalcemia. Arch. Neurol. 26 : 218 (1972).
Published
2017-06-13
How to Cite
1.
Hendarto S, Lazuardi S, Madyono B, Affandi M, Utama J. Spasmophilia. PI [Internet]. 13Jun.2017 [cited 4Dec.2024];18(3-4):109-6. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1468
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Received 2017-06-02
Accepted 2017-06-02
Published 2017-06-13
Accepted 2017-06-02
Published 2017-06-13
