The Quartan Malarial Nephrotic Syndrome

  • R. G. Hendrickse School of Tropical Medicine, Liverpool.
Keywords: quartan malarial, nephrotic syndrome.

Abstract

The Nephrotic Syndrome as classically described is a disease of unknown aetiology with a peak incidence in the first three years of life, highly selective proteinuria, minimal histological changes in the kidney and usually responsive to steroid therapy. Studies in tropical Africa in recent years have revealed a high incidence of the nephrotic syndrome in childhood which shows many differences from the syndrome as described elsewhere. The vast majority of cases occur in association with P. malariae infection, the peak incidence occurs at 5 - 6 years of age, proteinuria is usually poorly selective, distinctive histological changes are found in the majority and response to steroids, and other forms of treatment, is in general poor.

References

ADENIYI, A; HENDRICKSE, R.G. and HOUBA, V.: Lancet i:644 (1970).

ADERELE, W.L. and SERIKI, O. : Arch. Dis. Child. 49 : 313 (1974).

ALISON, A.C., HOUBA, V., HENDRICKSE, R.G., de PETRIS, EDINGTON, G.M. and ADENIYI, A.: Lancet ii : 1232 (1969).

ATKINSON, I.E. : Am. J. Med. Sci. 88 : 149 (1884).

CARROTHERS, J.C. : East Afr. Med. J. 10 : 335 (1934).

CHURG. J., HABIB, R. and WHITE, R.H.R. : Lancet 1 .1299 (1970).

DIXON, F.J. in Immunopathology, 2nd International Symposium; 17 (1962).

DIXON, F.J. : Milit. Med. 131, Suppl. 1233, p. 131 (1966).

EDINGTON, G.M. and MAINWARING, A.R. in The Kidney. (Int. Acad. Path. Monogr. No. 6, p. 488, 1966).

GIGIOLI, G. : Malarial Nephritis (Churchill, London 1930).

GIGLIOLI, G. : Ann. Trop. Med. Parasitol. 56 : 101, and 56 : 225 (1962).

GILLES, H.M. and HENDRICKSE R.G. : Br. Med. J. ii : 27 (1963).

HENDRICKSE, R.G. : 3rd Int. Congr. Nephrosis (Washington) Abstr. p. 208 (1966).

HENDRICKSE, R.G. (1964) — Unpublished data.

HENDRICKSE, R.G. and GILLES, H.M. : East Afr. Med. J. 40 : 186 (1963).

HENDRICKSE, R.G., GLASGOW, E.F., ADENIYI, A., WHITE, R.H.R., EDlNGTON, G.M. and HOUBA, V. : Lancet i : 1143 (1972).

HOUBA, V., Allison, A.C., HENDRICKSE, R.G., de PETRIS, S., EDINGTON, G.M. and ADENIYI, A. in Proc. Int. Symp. Immune Complex Dis. Bonomo & Turk, (1970).

HOUBA, V., ALLISON, A.C., ADENIYI, A. and HOUBA, J.E. : Clin. Exp. Immunol. 8 : 761 (1971).

HOUBA (1972). Personal Communication.

JAMES, C.S. : Med. J. Aust. I : 759 (1939).

LAMBERS, J.A. : Geneesk Tijdschr. Ned. Indie 72 : 334 (1932).

SENECAL, J., LARIVIERE, M., COUTURIER, P. and PANIS, J. : Bull. Soc. Med. Afr. Noire Lang. Fr. Dakar, 4 : 406 (1959).

SOOTHILL, J.F. and HENDRICKSE, R.G. : Lancet ii : 629 (1967).

WHITE, R.H.R., GLASGOW, E.F. and MILLS, R.J. : Lancet i : 1353 (1970).
Published
2017-05-29
How to Cite
1.
Hendrickse RG. The Quartan Malarial Nephrotic Syndrome. PI [Internet]. 29May2017 [cited 29Mar.2024];15(3-4):83-2. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1412
Received 2017-05-24
Accepted 2017-05-24
Published 2017-05-29