Bacterial endocarditis in children: clinical and laboratory findings, and the role of echocardiography in its diagnosis and management

  • Sudigdo Sastroasmoro Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Bambang Madiyono Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Ismet N. Oesman Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Sukman Tulus Putra Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Keywords: bacterial endocarditis, echocardiography, prolonged fever

Abstract

We report clinical and laboralory findings of 15 children with bacterial endocarditis, admitted ro the Department of Child Health, University of Indonesia/Cipto Mangunkusumo Hospital from February, 198710 June, 1989.

There were 8 boys and 7 girls with bacterial endocarditis, ranging in age from 10 weeks 10 16 years. The diagnosis was suspected because of prolonged fever, with or without other manifestations, i.e. congestive heart failure, refractory anemia, or paroxysmal atrial tachycardia. The underlying heart disease was congenital in 12 cases and rheumatic heart disease in 3 cases.

The clinical, electrocardiographic, and radiologic manifestations were generally predominated by the pre-existing heart disease. No characteristic findings of bacterial endocarditis, i.e. Osler's nodes, Janeway lesions or splinter haemorrhages were detected.

Positive bacterial culture was obtained in 12 cases; the most frequent bacteria isolated was Pseudomonas aeruginosa (4 cases), Streptococcus viridans was isolated in 2 cases only.

Vegetation was visualized echocardiographically in 12 cases; 9 with clear cut evidence of large vegetation, and the other 3 the vegetation was equivocal. On follow-up they disappeared gradually with clinical improvemenl. Large vegetation might need 2 full months 10 disappear echocardiographically.

References

1. CALDWELL, R.L.; SHACHAR, B; LIEBMAN. J.: Subacute bacterial endocarditis in infants and children: Current status. Amer. J. Dis. Child. 112: 312•316 (1971).
2. DILLON, J.C.; FIEGENBAUM, H.; KONECKE, L.; DAVIS, R.H.; CHANG, S.: Echocadiographic manifestations of valvular vegetations. Amer. Heart J. 86: 698-704 (1973).
3. GEVA. T.; FRAND. M.: Infective endocarditis in children with congenital heart disease: the changing spectrum, 1965-1985. Eur. Heart J. 9: 1244•1249 (1988).
4. JOHNSON, C.M.; RHODES, K.H.: Pediatric endocarditis. Mayo Clin. Proc:. 57: 86-92 (1982).
5. JOHNSON, D.H.; ROSENTHAL, A.; NADAS, A.S.: Bacterial endocarditis in children under 2 years of age. Amer. J. Dis. Child. 129: 183-186 (1975).
6. JOHNSON, D.H.; ROSENTHAL, A.; NADAS, A.S.: A forty-years review of bacterial endocarditis in infancy and childhood. Circulation 51: 581-580 (1979).
7. KAPLAN, E.L.; RICH, H.; GERSONY, W.; MANNING, J.: A collaborative study of infective endocarditis in the 1970's. Emphasis on infections who have undergone cardiovascular surgery. Circulation 59: 327-339 (1979).
8. KAPLAN, E.L.; SHUl.MAN, S.T.: Endocarditis; in ADAMS, EMMANOULIDES, Moss Heart Disease in Infants, children, and adolescents, 3rd. ed., pp. 565-576 (Williams & Wilkins, Baltimore/London 1983).
9. LUTAS, E.M.; ROBERTS, R.B.; DEREVEUX, R.B.; PRIETO, L.M.: Relation between the presence of echocardiographic vegetations and the complication rate in infective endocarditis. Amer. Heart J. 112: 107-113 (1986).
10. MELTZER, R.; ROELANDT, J.: Cardiac catheterization and echocardiography in infective endocarditis. Arner J. Cardiol. 47: 1183-1186 (1981).
11. MULLER-HAAKE, R.C.; MINALE . C.; STEINKAMP, H•J.; BARDOS, P.: The role of echocardiography in the diagnosis of acute infective endocarditis. Eur. Heart J. 8 (SUDDI): 293•298 (1987).
12. ROBBIN, M.J.; SOEIRO, R.; FRISHMAN, W.H.; STROM, J.A. : Right-sided valvular endocarditis: Etiology. diagnosis, and an approach to therapy. Amer. H.J. 111: 128-135 (1985).
13. WANN, L.S.; HALLAM, C.C.; DILLON, J.C.; WEIMAN, A.E.; F1EGENBAUM, IL Comparison of M-rnode and cross sectional echocardiography in infective endocarditis. Circulation 60: 728-734 (1979).
Published
1989-10-30
How to Cite
1.
Sastroasmoro S, Madiyono B, Oesman I, Putra S. Bacterial endocarditis in children: clinical and laboratory findings, and the role of echocardiography in its diagnosis and management. PI [Internet]. 30Oct.1989 [cited 26Apr.2024];29(9-10):188-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1292
Received 2017-02-23
Accepted 2017-02-23
Published 1989-10-30