Factors associated with mortality in newborn infants with meconium aspiration syndrome

  • Asril Aminullah Department of Child, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Jonardi Sarmili Department of Child, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Sudigdo Sastroasmoro Department of Child, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Keywords: meconium aspiration syndrome, risk faclors, infants morbidity and mortality

Abstract

Meconium aspiration syndrome (MAS) is still one of the common causes of morbidity and mortality in neonatal period. A retrospective study was conducted from January 1993 to December 1999, to identify factors associated with mortality in MAS. Univariate analysis disclosed that preeclampsia/eclampsia, sex, Apgar scores, consistency of meconium, and use of mechanical ventilation were significantly associated with mortality in MAS, while gestational age, mode of delivery, hypertension, birth weight, tracheal suctioning, blood cultures, and complications were not. Logistic regression analysis showed that mode of delivery, preeclampsia/eclampsia, Apgar scores, consistency of meconium, and use of mechanical ventilation were associated with mortality in MAS, while other variables were not.

References

1. Wiswell TE. Bent RC. Meconium staining and the meconium aspiration syndrome: unresolved issues. Pediatr Clin North Am. 1993;40:955-81.
2 Adhikari M, Gouws E, Velaphi SC. Gwamanda P. Meconium aspiration syndrome: importance of the monitoring of labor. J Perinatol. 1998 ;18:55-60.
3. Carson BS. Suctioning the meconium-stained infant. Am J Dis Child. 1988;142; 698-9.
4. Eichenwald EC. Meconium aspiration. In: Creasy RK, Resnik R, editors. Manual of neonatal care. 4th edition. Philadelphia: Lippincott; 1998. p. 388-91.
5. Vidyasagar D, Andreou A. Management of meconium aspiration syndrome. In: Aladjem S, Brown AK. editors. Perinatal intensive care. St. Louis: Mosby; 1977. p. 4 13-25.
6. Meis PJ. Hall M, Marshall JR, et al. Meconium passage: a new classification for risk assessment labor. Am J Obstet GynecoI. 1978;131:509-13.
7. Rossi EM, Philipson EH. Williams TG. Kalhan SC. Meconium aspiration syndrome: intrapartum and neanatal atributes. Am J Obstet Gynecol. 1989;161: 1106-10.
8. Zuspan FP. Hypertensive disorders of pregnancy. In: Fanaroff AA, Martin RJ, editors. Neonatal perinatal medicine. Disease of the fetus and infant. 6th edition. St. Louis: Mosby; 1997. p. 241-57.9.
9. Katz VL. Bowes WA. Meconium aspiration syndrome: reflection on a murky subject. Am J Obstet Gynecol. 1992;166: 171-83.
Published
2017-02-08
How to Cite
1.
Aminullah A, Sarmili J, Sastroasmoro S. Factors associated with mortality in newborn infants with meconium aspiration syndrome. PI [Internet]. 8Feb.2017 [cited 20May2024];41(1-2):6-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1256
Received 2017-02-06
Accepted 2017-02-06
Published 2017-02-08