Main Article Content
Childhood tuberculosis persists as an important global health problem. Tuberculosis is one of the commonest
important complications in children with nephrotic syndrome. Tuberculosis may interfere with the response to steroid therapy
and is still being the commonest morbidity cause in children with nephrotic syndrome. To find out the prevalence, clinical
features, and the impact of tuberculosis in children with nephrotic syndrome, a cross sectional study was conducted on 100
nephrotic children consisted of 63 males and 37 females at the Cipto Mangunkusumo Hospital from April 1st to October 30th,
1999. Pulmonary tuberculosis was detected on 15 cases ( 95% CI : 8% - 22% ) , consisted of 8 boys and 7 girls. Most of them
aged 10 – 16 years old (66,6%) and 86,7% were undernourished. The combination of clinical judgement, chest X-ray and
Mantoux test were helpful in establishing the diagnosis. The majority of tuberculosis cases (80%) were detected on frequent
relapsers and steroid dependent groups of the nephrotic syndrome. A significant correlation were noted in tuberculosis with
undernutrition and unfavorable response to steroid (frequent relapser and steroid dependent cases).
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