Diagnosis of pediatric tuberculosis using The Indonesian National Concencus for Pediatric Tuberculosis

  • Heda Melinda D. Nataprawira Department of Child Health, Universitas Padjadjaran Medical School/Dr. Hasan Sadikin General Hospital, Bandung, West Java
  • Cissy B. Kartasasmita Department of Child Health, Universitas Padjadjaran Medical School/Dr. Hasan Sadikin General Hospital, Bandung, West Java
  • Oma Rosmayudi Department of Child Health, Universitas Padjadjaran Medical School/Dr. Hasan Sadikin General Hospital, Bandung, West Java
  • Hudiyati Agustini Medical Research Unit, Universitas Padjadjaran Medical School/Dr. Hasan Sadikin General Hospital, Bandung, West Java
Keywords: diagnosis, pediatric TB, Indonesian National Consensus

Abstract

Diagnosing tuberculosis (TB) in children correctly is critical to appropriate treatment. However, diagnosing TB in children may be difficult and can be imprecise. As our national TB control program has not adequately covered TB in children and adult TB cases still in high rank, our national consensus for pediatric population may facilitate TB diagnosed especially in the field. This cross sectional study as part of longitudinal cohort study of epidemiology of Respiratory Syncitial Virus (RSV) in Indonesia (still ongoing) was conducted to know whether criteria used in the algorithm in the consensus compatible to suspected TB diagnosis. The study covered 1000 children under five randomly selected in two districts (Cikutra and Ujung Berung Indah) located in West Java. By using algorithm of The Indonesian National Consensus For Pediatric Tuberculosis (INCPT) with history of known or suspected adult source of TB or early reaction of BCG vaccination and certain general clinical symptoms associated TB as entry criteria for a higher index of suspicion, we diagnosed suspected TB in 57 children. We found that, history of known or suspected adult source of TB and certain general clinical symptoms are two main criteria for suspected TB diagnosis. It appeared that Mantoux test gave a smallest contribution to the diagnosis of suspected TB in the field. No other criterium except known or suspected adult source of TB fulfilled for other five children and prophylactic treatment for TB were given. Those children with suspected TB were given oral anti-tuberculosis (OAT) by Directly Observed Treatment Short course (DOTS) done by local trained persons.

 

References

1. Aditama TY. Prevalence of tuberculosis in Indonesia, Singapore, Brunei Darussalam and the Philippines. Tubercle 1991;72: 255-60.
2. Sudre P, ten Dam G, Kochi A. Tuberculosis: a global overview of the situation to day. WHO Bull OMS 1992;70: 149-59.
3. Beyers N, Gie RP, Schaaf S, et al. A prospective evaluation of children under the age of 5 years living in the same household as adults with recently diagnosed pulmonary tuberculosis. Int J Tuberc Lung Dis 1997;1: 38-43.
4. Pio A, Luelmo F, Kumaresan J, Spinaci S. National tuberculosis program review: experience over the period 1990-95. WHO Bull OMS 1997;75:569-81.
5. Schutze GE, Jacobs RF. Tuberculosis in children: Where we stand today. J Respir Dis 1993;14: 1326-41.
6. Driver CR, Luallen JJ, Good WE, Valway SE, Frieden TR, Onorato IM. Tuberculosis in children younger than five years old: New York City. Pediatr Infect Dis J 1995;14: 12-7.
7. Starke JR, Watts KT. Tuberculosis in the pediatric population of Houston, Texas. Pediatrics 1989;84: 28-35.
8. Neu N, Saiman L, San Gabriel P, et al. Diagnosis of pediatric tuberculosis in the modern era. Pediatr Infect Dis J 1999;18:122-6.
9. Osborne CM. The challenge of diagnosing childhood tuberculosis in a developing countries. Arch Dis Child 1995;72: 369-74.
10. International Union against Tuberculosis and Lung Disease. Tuberculosis in children. Guidelines for diagnosis, prevention and treatment. Bull Int Union Tuberc Lung Dis 1991; 66: 61-7.
11. Dommisse J. Undiagnosed primary tuberculosis as a possible major cause of a high infant/child mortality rate. The J of Trop and Environmental Child Health 1975;21: 307-10.
12. Houwert KAF, Borggreven PA, Schaaf HS, Nel E, Donald PR, Stolk. Prospective evaluation of World Health Organization criteria to assist diagnosis of tuberculosis in children. Eur Respir 1998;11: 1116-20.
13. Klein M, Iseman M. Mycobacterial infections. In: Taussig LM and Landau LI (eds). Pediatric respiratory medicine. St Louis: Mosby, 1999. P. 702-32.
14. Steiner P, Rao M, Victoria MS, Jabbar H, Steiner M. Persistently negative tuberculin reactions. Their presence among children with culture positive for Mycobacterium tuberculosis (Tuberculin-negative tuberculosis). Am J Dis Child 1980;134: 747-50.
15. Ibe M, Miyame T, Katakura S, ey al. Analysis of tuberculin reaction of tuberculous children below 4 years of age. Kansenshogaku Casshi 1999;73 (7): 658-63.
16. Fourie PB, Becker PJ, Festenstein F, Migliori GB, et al. Procedures for developing a simple scoring method based on unsophisticated criteria for screening children for tuberculosis. Int J Tuberc Lung Dis 1998;2(2): 116-23.
Published
2001-08-30
How to Cite
1.
Nataprawira H, Kartasasmita C, Rosmayudi O, Agustini H. Diagnosis of pediatric tuberculosis using The Indonesian National Concencus for Pediatric Tuberculosis. PI [Internet]. 30Aug.2001 [cited 9May2024];41(7-8):185-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1072
Section
Articles
Received 2016-11-22
Accepted 2016-11-22
Published 2001-08-30