Clinical and laboratory features of children with insulin dependent diabetes mellitus of more than two years

  • Jose R. L. Batubara Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangukusumo Hospital, Jakarta
  • Agus Firmansyah Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangukusumo Hospital, Jakarta
  • Riza Mansyoer Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangukusumo Hospital, Jakarta
  • Bambang Tridjaja Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangukusumo Hospital, Jakarta
  • Aman B. Pulungan Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangukusumo Hospital, Jakarta
Keywords: Insulin dependent diabetes mellitus, IDDM, blood glucose home monitoring, insulin, metabolic control

Abstract

The incidence rate of IDDM in our clinic during the period from 1989 to 1998 was 0.028%. There were twentyfour IDDM patients with duration of illness of more than 2 years, with a male to female ratio of 1: 1.5. Most of these patients had no diabetic family history and had good nutritional status. The insulin dosage used by these patients ranged between 0.67 - 0.72 IU/kg/day with a mean of 1.06 IU/kg/day. The average frequency of blood glucose home monitoring was less than ideal. Twenty-two out of the 24 patients were fully controlled metabolically; however, these patients still have polyuria, polydipsia, and polyphagia.

References

1. World Health Organization. Prevention of diabetes mellitus. WHO Tech Rep Ser; Geneva: 1994.
2. Andi Wijaya. Pemeriksaan laboratorium untuk diagnosis dan pengelolaan diabetes melitus. Prodia Diagnostic Educational Services, 1997; 1: 1-16.
3. Arslanian S, Becker D, Drash A. Diabetes mellitus in the child and adolescents. In: Kappy MS, Blizzard RM, Migeon CJ, editors. The diagnosis and treatment of endocrine disorders in childhood and adolescence. 4th ed. Illinois: Charles C Thomas; 1994. p.961-1024.
4. Travis LB, Brouhard BH, Schreiner BJ. Diabetes mellitus in children and adolescents. Philadelphia: Saunders; 1987. p.18-72.
5. Batubara JR. Perbedaan penanganan diabetes pada anak. In: Soegondo S, Soewondo P, Subekti I, editors. Diabetes melitus penatalaksanaan terpadu. Jakarta: FKUI, 1995. p.180-9.
6. World Health Organization. WHO expert committee on diabetes mellitus. WHO Tech Rep Ser; Geneva: 1980.
7. Batubara JRL, Tridjaja B, Pulungan A, Riza. Gambaran klinis dan laboratoris DMTI pada anak saat pertama kali datang ke Bagian IKA-RSCM. Presented at Kongres Nasional Perkumpulan Endokrinologi Indonesia V, Bandung, April 9-13, 2000.
8. Yang Z, Wang K, Li T dkk. Childhood diabetes in China enormous variation by place and ethnic group. Diabetes care 1998; 21: 525-9.
9. Menon PSN, Viramani A, Shah P dkk. Childhood onset diabetes mellitus in India: an overview, Int J Diab Dev Countries, 1990; 10: 11-6.
10. Dorchy H, Roggemans MP, Willems D. Glycated hemoglobin and related factors in diabetic children and adolescents under 18 years of age: a Belgian experience. Diabetes care 1997; 20: 2-6.
11. Sutan Assin M, Rukman Y, Batubara JR. Childhood onset of diabetes mellitus report on hospital cases. Pediatr Indones 1990; 30: 209-12.
12. Komulainen J, Kulmala P, Savola K, dkk. Clinical, autoimmune and genetic characteristics of very young children with type 1 diabetes. Diabetes care 1999; 22: 1950-5.
13. Mac Laren NK, Riley WS, Silverstein JH. Insulin dependent diabetes: inherited susceptibility natural history and intervention trials. Acta Ped Jpn 1987; 29: 24-30.
14. Nazir, Sidartawan, Waspadji S, dkk. Pola penderita diabetes melitus usia muda di Poliklinik Metabolik Endokrin Ilmu Penyakit Dalam RSCM Jakarta. Presented at Kongres Nasional Perkumpulan Endokrinologi Indonesia I, Jakarta November 22-25, 1986.
15. Bloch CA, Clemons P, Spelling MA. Puberty decreases insulin sensitivity. J Pediatr 1987; 110: 481-6.
Published
2006-10-30
How to Cite
1.
Batubara J, Firmansyah A, Mansyoer R, Tridjaja B, Pulungan A. Clinical and laboratory features of children with insulin dependent diabetes mellitus of more than two years. PI [Internet]. 30Oct.2006 [cited 22Nov.2024];41(9-10):256-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1066
Received 2016-11-22
Accepted 2016-11-22
Published 2006-10-30