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We reviewed patents with retinoblastoma treated at the Department of Child Health, Adam Malik Hospital, Medan from January 1995 to December 1999. Clinical staging was based on Reese-Ellsworth classification (when the disease was limited to the eyeball) or on St Jude Children's Research Hospital (when the disease has extended beyond the eyeball). A total 19 retinoblastoma patients were available, from which 9 were males. Fifteen patients were less than 5 years old, and the average age at diagnosis was 3 years 8 months. In most patients the disease started at the age of less than 5 years, and they presented themselves with advanced stage as usually seen in developing countries. In nine patients the retinoblastoma affected the right eye, 8 affected the left eye, and in 2 patients the tumor was bilateral. The most common presenting symptom on admission was proptosis. Pathological confirmation was obtained in all patients. Bone marrow puncture was done in 15 patients; of whom 13 showed bone marrow metastasis. Since 1998 the standard treatment for patients with proptosis in stage III or IV of the disease was pre-operative chemotherapy followed by enucleation, radiation and chemotherapy.
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Lippincott; 1997. p. 699-715.
2. Pratt CB. Retinoblastoma. In: Behrman RE, Kliegman RM, Arvin AM, editors. Nelson textbook of pediatrics. 15th ed. Philadelphia: Saunders; 1996. p. 1470-1.
3. Shields JA, Shields CL. Current management of retinoblastoma. Mayo Clin Proc 1994; 69:50-6.
4. Rudolph AM, Hoffman JIE, Rudolph CD, editors. Rudolph's Pediatrics, 20th ed. San Fransisco: Prentice Hall Int; 1996; 2:105.
5. Jones PG, Campbell PE. Tumors of infancy and childhood. 1st ed. Melbourne: Blackwell; 1976. p. 423-34.
6. O'Keefe M. Retinoblastoma. In: Puri P, editor. Neonatal tumours. 1st ed. Berlin: Springer; 1996. p. 89-94.
7. Jones PG. Clinical paediatric surgery. Diagnosis and management. 2nd ed. Melbourne: Blackwell; 1976. p. 175-6.
8. Nasution R, Sutjipto A. Childhood retinoblastoma. Paediatr Indones 1991; 31:117-22.
9. Voute P. Childhood cancer. Course & Workshop. The 2nd basic sciences in oncology and the 4th Paediatric Oncology, Jakarta, April 12-15th, 2000.