Rupture of esophageal varices due to portal hypertension
Abstract
Variceal bleeding is the most common cause of serious upper gastrointestinal (UGI) bleeding in children. Most variceal bleeding is esophageal.1 Hemorrhages from esophageal varices due to portal hypertension are a major cause of morbidity and mortality. There is a 30% mortality rate following an initial episode of variceal hematemesis. Mortality increases to 70% with recurrent variceal hemorrhage. Moreover, the one year survival rate after variceal hemorrhage is often poor (32 to 80%).2-4 We report a case of esophageal varices rupture caused by portal hypertension, an emergent case in the Pediatric Gastrohepatology division.
References
2. Orenstein S. Esophageal varices. In: Nelson WE, Kliegman RM, Jenson HB, editors. Textbook of pediatrics. 18th ed. Philadelphia, Saunders; 2004. p. 1225-6.
3. Sawant PD, Nanivadekar SA, Desai DC, Kanakia RK, Rajgopalan K, Dave UK. Long tenn follow up of endoscopic sclerotherapy. Indian Pediatr. 1994;31:1443-6.
4. Genecin P, Groszmann RJ. Portal hypertension. In: Schiff L, Schiffre, editors. Diseases of the liver. 7th ed. Philadelphia: JB Lippincott; 1993. p. 935-73.
5. Ament ME. Diagnosis and management of upper gastrointestinal tract bleeding in the pediatric patients. Pediatr Rev. 1990;12:107-14.
6. Suchy FJ. Portal hypertension and varices. In: Nelson WE, Kliegman RM, Jenson HB, editors. Textbook of pediatrics. 18th ed. Philadelphia, WB Saunders; 2004. p. 1709-11.
7. Boyle JT. Gastrointestinal bleeding in infants and children. Pediatr Rev. 2008;29:39-52.
8. Besson I, Ingrand P, Person B, Boutroux D, Heresbach D, Bernard P, et al. Sclerotherapy with or without octreotide for acute variceal bleeding. N Eng J Med. 1995;333:555-60.
9. Dib N, Oberti F, Cales P. Current management of the complications of portal hypertension : variceal bleeding and ascites. Can Med Assoc J. 2006;174:1433-43.
10. Gonzalez R, Zamora J, Camarero J G, Molinero LM, Bafiares R, Albillos A. meta-analysis: combination endoscopic and drug therapy to prevent variceal re-bleeding in cirrhosis. Ann Intern Med. 2008;149:109-22.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Accepted 2016-11-07
Published 2010-10-30