Anemia in children with chronic renal failure Special attention erythrocyte indices and iron deficiency anemia

  • Adi Suryanto B
  • Partini P Trihono
  • Agus Firmansyah
Keywords: chronic renal failure, anemia, iron deficiency

Abstract

Background Anemia in chronic renal failure (CRF) has been
proved to influence the quality of life, increasing morbidity and
mortality. Early diagnosis and prompt treatments of anemia are
mandatory to manage CRF appopriately. So far data of anemia in
CRF in Indonesia is limited.
Objective To find out the profile of anemia in children with CRF at
Cipto Mangunkusumo Hospital (CMH), Jakarta, with special atten-
tion in erythrocyte indices and iron deficiency anemia.
Methods Cross-sectional descriptive study was carried out on
patients with CRF and anemia in CMH since October 2003 to April
2004.
Results There were 20 CRF patients, aged between 1 year 3 month-
15 year old, mostly were above 10 year old, 11 patients were males
and 9 were females. The most frequent etiologies were urinary
tract infection (UTI) in 10 cases and nephrotic syndrome in 6 cases.
Of those 20 patients, 14 suffered from anemia with erythrocyte
indices, normochrome normocytic in 9 patients and hypochrome
microcytic in 5 patients. Of 14 anemic patients only 1 patient suf-
fered from iron deficiency anemia of less than 10 mg/l and transferin
saturation of less than 12%. Based on serum iron (SI) concentra-
tion only, 7 patients were diagnosed as having iron deficiency ane-
mia.
Conclusion Most patients with chronic renal failure have
normochrome normocytic anemia. Hypochromic microcytic iron
deficiency anemia is scarcely found in this group of patients.

Author Biographies

Adi Suryanto B
Department of Child Health, Medical School, University of
Indonesia, Jakarta, Indonesia.
Partini P Trihono
Department of Child Health, Medical School, University of
Indonesia, Jakarta, Indonesia.
Agus Firmansyah
Department of Child Health, Medical School, University of
Indonesia, Jakarta, Indonesia.

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Published
2016-10-18
How to Cite
1.
B A, Trihono P, Firmansyah A. Anemia in children with chronic renal failure Special attention erythrocyte indices and iron deficiency anemia. PI [Internet]. 18Oct.2016 [cited 29Mar.2024];46(4):154-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/920
Section
Articles
Received 2016-10-14
Accepted 2016-10-14
Published 2016-10-18